Angela received an MFA in Acting from the Graduate Acting Program at NYU Tisch School of the Arts. During those formative years, she was exposed to a variety of acting methods and was fortunate to work with such greats as Grotowski, Lloyd Richards, David Mamet, Andre Gregory, Kristen Linklater ,and Olympia Dukakis. Upon graduation, she helped form The Manhattan Project Theater Company under the direction of Andre Gregory. Ms Pietropinto made her first professional appearance in the title role of their Obie-winning production of Alice in Wonderland. During its eight-year existence, the company toured four continents and was the recipient of 2 Drama Desk awards and an Obie Award. Since then she has enjoyed a career in leading and featured roles on and off-Broadway, and in regional theater, television, and film.

In 1980, Ms. Pietropinto made her Broadway debut opposite Derek Jacobi in The Suicide and returned to Broadway for Eastern Standard and Tartuffe Born Again. Ms. Pietropinto has appeared off-Broadway at the Public Theater, Manhattan Theatre Club, Playwrights Horizons, Theatre Four, Lincoln Center Directors Lab, Minetta Lane Theatre, the Cherry Lane Theatre, the Ensemble Studio Theatre, and La Mama. Regionally, Ms. Pietropinto has acted at Yale Rep, the White Barn, and the O'Neill Playwrights Conference in Connecticut, at McCarter and GeorgeStreet Playhouse in New Jersey, and at the Wilma in Philadelphia.

On film Ms. Pietropinto portrayed Marj Wiener, the mother from hell, in Todd Solondz's Welcome to the Dollhouse, which won the 1995 Sundance Grand Jury Prize; she reprised the role for Mr. Solondz's most recent film, Palindromes. Other film credits include Shaft opposite Samuel L. Jackson (director - John Singleton), Nobody's Fool opposite Paul Newman (director - Robert Benton), Goodfellas opposite Paul Sorvino (director- Martin Scorsese), So Fine opposite Jack Warden (director - Andrew Bergman), Without a Trace (director- Stanley Jaffe), Running on Empty (director - Sidney Lumet), Heartburn opposite Jack Nicholson (director - Mike Nichols), It Could Happen to You, and Honeymoon in Vegas opposite Sarah Jessica Parker (director- Andrew Bergman), Stay (director- Marc Forster), and  Looking for Kitty (director- Edward Burns). The independent films, A Tale of Two Pizzas, which won the Audience Favorite Prize at the Sarasota Film Festival, and Little Kings have screened at film festivals both here and in Italy.  Her performances in 240 Monroe and Suffer the Little Children garnered her nominations in the best actress category on the Independent Film circuit.

On the little screen she has played an assortment of moms, doctors, lawyers, secretaries, and nuns on Law & Order, Criminal Intent, SVU, Third Watch , LateLine, Mad About You, The Cosby Show, Chappelle's Show, New York Undercover, The Jury, Rescue Me, and The Sopranos. Soap fans may remember her as Jean Slocum on All My Children or Connie Corelli on Another World.

Ms. Pietropinto received her training as a teaching artist at Lincoln Center Institute and has worked in the public school system under the auspices of Theatre Development Fund, Manhattan Theatre Club, and the Roundabout for many years.  She has taught at Yale Drama School and has been on the faculty of NYU Tisch School of the Arts for more than 12 years.